分析玻璃体切割与内界膜剥离术联合治疗黄斑裂孔性视网膜脱落的有效性及安全.docxVIP

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分析玻璃体切割与内界膜剥离术联合治疗黄斑裂孔性视网膜脱落的有效性及安全

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司南

【摘要】目的：观察并分析玻璃体切割与内界膜剥离术联合治疗黄斑裂孔性视网膜脱落的有效性及安全。方法：选取我院2016年6月至2019年6月接诊的52例黄斑裂孔性视网膜脱落（MHRD）患者，采用抽签方式将患者分为观察组和对照组，每组各26例患者。对照组患者接受玻璃体切割术（PPV），观察组患者在此基础上联合内界膜剥离术（ILMP）治疗，观察两组患者治疗后一个月视力改善情况、黄斑裂孔闭合情况以及并发症发生率（晶状体浑浊、眼压升高、视野缺损）。结果：观察组患者黄斑裂孔闭合率为95.15%，对照组闭合率为50%;观察组患者视力改善率为92.30%，对照组改善率为46.15%;观察组患者并发症发生率为7.69%，对照组为100%;P0.05，存在统计学意义。结论：玻璃体切割联合内界膜剥离术对于治疗黄斑裂孔性视网膜脱落，能够有效提高黄斑裂孔闭合率及术后患者视力改善情况，值得临床全面推广使用。

【关键词】黄斑裂孔性视网膜脱落;内界膜剥离术;玻璃体切割

Abstract：ObjectiveToobserveandanalyzetheefficacyandsafetyofvitrectomyandinternallimitingmembranepeelinginthetreatmentofmacularholeretinaldetachment.METHODS：Atotalof52patientswithmacularholeretinaldetachment（MHRD）whowereadmittedtoourhospitalfromJune2016toJune2019wereenrolled.Thepatientsweredividedintoobservationgroupandcontrolgroupbyweighting，with26patientsineachgroup.Thepatientsinthecontrolgroupunderwentvitrectomy（PPV）.Thepatientsintheobservationgroupweretreatedwithinternallimitingmembranestripping（ILMP）.Thevisualacuityimprovement，macularholeclosureandcomplicationratewereobservedinthetwogroupsaftertreatment.（Thelensiscloudy，theintraocularpressureiselevated，andthevisualfieldisdefective）.Results：Themacularholeclosureratewas95.15%intheobservationgroupand50%inthecontrolgroup.Thevisualacuityimprovementratewas92.30%intheobservationgroupand46.15%inthecontrolgroup.Thecomplicationrateintheobservationgroupwas7.69%.Thecontrolgroupwas100%;P0.05，whichwasstatisticallysignificant.Conclusion：Vitrectomycombinedwithinternallimitingmembranedissectionforthetreatmentofmacularholeretinaldetachmentcaneffectivelyimprovethemacularholeclosurerateandpostoperativevisionimprovement，itisworthyofclinicalpromotion.

Keywords：macularholeretinaldetachment;internallimitingmembranepeeling;vitrectomy

R77A1005-0019（202