磁共振在胰腺神经内分泌肿瘤诊断中的应用1.docxVIP

??

?

??

磁共振在胰腺神经内分泌肿瘤诊断中的应用

?

??

?

?

?

?

?

?

?

???

?

?

?

?

?

[摘要]目的评价3.0T磁共振在胰腺神经内分泌肿瘤诊断中的应用价值。方法回顾性分析6例经手术病理证实的胰腺内分泌肿瘤的患者，比较T1WI，T2WI，DWI和动态增强四个序列对病灶的显示情况。结果6例患者中，其中1例有5个病灶，共10例病灶。病灶最大径平均值为2.12cm，在T1WI中3例低信号，5例稍低信号，2例等信号。在T2WI中6例高信号，2例稍高信号，2例信号不均匀，表现为等/高混杂信号；DWI中，去除囊变坏死等部分，10例均为高信号。动态增强方式有以下几种：6例病灶整个动态扫描周围表现为均匀轻中度强化，2例病灶动脉期中度或明显均匀强化，门脉和延迟期有所下降但仍高于周围正常胰腺实质信号，2例病灶中央明显囊变坏死，囊变坏死区无强化，周围呈持续性环状强化。结论多数胰岛细胞瘤TIWI上表现为等低信号，T2WI上表现为高信号，DWI上均表现为高信号，动态增强上MRI动脉期明显强化。?[关键词]胰腺肿瘤；神经内分泌肿瘤；磁共振成像；扩散加权成像?[Abstract]ObjectiveToevaluatethevalueof3.0TMRinthediagnosisofpancreaticneuroendocrinetumors.Methodssixpatientswithpancreaticendocrinetumorconfirmedbyoperationandpathologywereanalyzedretrospectively.TheresultsofT1WI,T2WI,DWIanddynamicenhancementwerecompared.Resultsamongthe6patients,1had5lesions,10lesionsintotal.Theaveragediameterofthelesionswas2.12cm.InT1WI,3caseswerelowsignal,5caseswereslightlylowsignal,2caseswereequalsignal.InT2WI,therewere6casesofhighsignal,2casesofslightlyhighsignal,2casesofunevensignal,showingequal/highhybridsignal;inDWI,10caseswereallhighsignal.Thedynamicenhancementmethodswereasfollows:6casesshowedhomogeneouslighttomoderateenhancementaroundthewholedynamicscanning,2casesshowedmoderateorobvioushomogeneousenhancementinthearterialphase,decreasedintheportalveinanddelayphase,butstillhigherthanthesignalofsurroundingnormalpancreaticparenchyma,2casesshowedobviouscysticnecrosisinthecenter,noenhancementinthecysticnecrosisarea,andcontinuousannularenhancementaround.ConclusionmostisletcelltumorsshowisolowsignalonTiwi,highsignalonT2WIandhighsignalonDWI.Ondynamiccontrast-enhancedMRI,thearterialphaseissignificantlyenhanced.

[Keywords]pancreaticneoplasms;neuroendocrineneoplasms;magneticresonanceimaging;diffusionweightedimaging

为评价3.0T磁共振在胰腺