“益肾补虚化瘀散结法”治疗慢性小球肾炎60例临床研究的开题报告.pdfVIP

“益肾补虚化瘀散结法”治疗慢性小球肾炎60例临

床研究的开题报告

摘要

慢性小球肾炎是一种常见的肾脏疾病，其病理特点是肾小球的慢性

炎症反应，长期进展可导致肾功能受损。传统中药治疗在临床上有较好

的应用，其中益肾补虚化瘀散结法通常被用作治疗慢性小球肾炎。本研

究旨在探讨益肾补虚化瘀散结法治疗慢性小球肾炎的效果和安全性。

先行研究表明，益肾补虚化瘀散结法在治疗慢性小球肾炎方面有显

着的效果，且较为安全。本研究将招募60名慢性小球肾炎患者，随机分

为治疗组和对照组，治疗组将接受益肾补虚化瘀散结法治疗，对照组将

接受常规治疗。治疗时间为12周，观察指标包括肾功能、尿白蛋白/肌

酐比值、血压、临床症状与生活质量等。

预计本研究结果将对益肾补虚化瘀散结法在慢性小球肾炎治疗中的

应用进行客观评估，为慢性小球肾炎的中药治疗提供有力支持和参考。

关键词：慢性小球肾炎；中药治疗；益肾补虚化瘀散结法；效果和

安全性

Abstract

Chronicglomerulonephritisisacommonkidneydisease,

characterizedbychronicinflammationoftheglomerulus,whichcan

leadtorenaldysfunction.TraditionalChinesemedicinehasbeenwidely

usedintheclinicaltreatmentofchronicglomerulonephritis,andthe

methodofnourishingkidney,tonifyingdeficiency,promotingblood

circulationandremovingbloodstasisisusuallyusedtotreatchronic

glomerulonephritis.Thepurposeofthisstudyistoexplorethe

effectivenessandsafetyofthismethodintreatingchronic

glomerulonephritis.

Previousstudieshaveshownthatthismethodhassignificant

therapeuticeffectonchronicglomerulonephritisandisrelativelysafe.

Thisstudywillrecruit60patientswithchronicglomerulonephritis,who

willberandomlydividedintotreatmentgroupandcontrolgroup.The

treatmentgroupwillreceivethemethodofnourishingkidney,tonifying

deficiency,promotingbloodcirculationandremovingbloodstasis,while

thecontrolgroupwillreceiveconventionaltreatment.Thetreatment

timeis12weeks,andtheobservedindicatorsincluderenalfunction,

urinaryprotein/creatinineratio,bloodpressure,clinicalsymptomsand

qualityoflife.

Theresultsofthisstudyareexpectedtoprovideanobjective

evaluationoftheapplicationofthemethodofnourishingkidney,

tonifyingdeficiency,promotingbloodcirculationandremovingblood

stasisinthetreatmentofchronicglomerulonephritis,andprovide

strong