2S-3-Keto-sphinganine-d6-0-hydrochloride-2S-3-Keto-C6-dihydrosphingosine-hydrochloride-生命科学试剂-MCE.pdf

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(2S)-3-Ketosphinganine(d6:0)(hydrochloride)

Cat.No.:HY-165975

CASNo.:1314999-30-8

Synonyms:(2S)-3-Keto-C6-dihydrosphingosinehydrochloride

分⼦式:C₆H₁₄ClNO₂

分⼦量:167.63

作⽤靶点:Liposome

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性(2S)-3-Ketosphinganine(d6:0)((2S)-3-Keto-C6-dihydrosphingosine)hydrochloride是⼀种脂质类化合物

，可⽤于脂质体制备。脂质体是具有同⼼磷脂双层膜囊泡的主要成分，可以构建出⽤于抗癌和抗感染领域的药

物递送系统。⾼极性的⽔溶性载荷可以被捕获在脂质体的内部⽔性空间中，⽽亲脂性载荷可以分配到脂质双层

中并成为脂质双层的⼀部分。特别是⽤于递送反义寡核苷酸，能够克服细胞摄取低效和体内流失快等问题。

REFERENCES

[1].JulianoRL,etal.Liposomesasadrugdeliverysystemforantisenseoligonucleotides[J].Antisenseresearchanddevelopment,1992,

2(2):165-176.

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