1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine-18-0-22-6-PE-生命科学试剂-MCE.pdf

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1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine

Cat.No.:HY-157624

CASNo.:96998-01-5

Synonyms:18:0-22:6PE

分⼦式:C₄₅H₇₈NO₈P

分⼦量:792.08

作⽤靶点:Liposome

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Solution,-20°C,protectfromlight,2years

*Insolvent:-80°C,6months;-20°C,1month(protectfrom

light,2years)

BIOLOGICALACTIVITY

⽣物活性1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine(18:0-22:6PE)是⼀种脂质类化合物，可

⽤于脂质体制备。脂质体是具有同⼼磷脂双层膜囊泡的主要成分，可以构建出⽤于抗癌和抗感染领域的药物递

送系统。⾼极性的⽔溶性载荷可以被捕获在脂质体的内部⽔性空间中，⽽亲脂性载荷可以分配到脂质双层中并

成为脂质双层的⼀部分。特别是⽤于递送反义寡核苷酸，能够克服细胞摄取低效和体内流失快等问题。

REFERENCES

[1].JulianoRL,etal.Liposomesasadrugdeliverysystemforantisenseoligonucleotides[J].Antisenseresearchanddevelopment,1992,

2(2):165-176.

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