99Tcm-MDP全身骨显像联合血清PSA检测在前列腺癌骨转移诊断中的意义.pdf

《中国医学前沿杂志(电子版)》2014年第6卷第7期·论著·93

TCm-MDP全身骨显像联合血清PSA检

测在前列腺癌骨转移诊断中的意义

庞华，高洪波，孙晓光3刘海春2刘建通，张曙光(1．中国核工业北京四。一医院外科，北京

102413；2．中国核工业北京四。一医院核素诊疗中心，北京102413；3．河北唐县人民医院外科，

河北唐县067203)

【摘要】目的探讨TCm-MDP全身骨显像与血清前列腺特异性抗原(PSA)诊断前列腺癌骨转移的临

床价值。方法对60例经临床确诊的前列腺癌患者行TCm-MDP全身骨显像及血清PSA测定，并对

骨转移与PSA水平进行相关性分析。结果前列腺癌患者骨转移的发生率为72．5％。前列腺癌骨转移

组和非骨转移组患者的PSA水平比较差异有显著性(P0．05)。随着骨显像分级升高，血清PSA水

平逐渐升高，且两者呈正相关。PSA20ng／ml时患者骨转移发生率为90．7％，而PSA≤20ngm／l时，

患者骨转移发生率为35．3％。结论TCm-MDP全身骨显像与血清PSA联合检测对前列腺癌的临床诊

断具有重要指导意义，血清PSA水平与前列腺癌骨转移程度呈正相关。

【关键词】前列腺癌；骨转移；TCm-MDP全身骨显像；PSA

”T一MDPwholebodyboneimagingcombinedwithserumPSAtestinginthediagnosisofprostate

cancerbonemetastases

PANGHua，GAOHong_bO，SUNXiao—guang，LIUHai—chun，LIUJian—tong，ZHANGShu—guang

(1．DepartmentofSurgery，Beijing401HospitalofChineseNuclearIndustry，Beijing102413，China；

2．DepartmentofRadionuclideTreatmentCenter,Beijing401HospitalofChineseNuclearIndustry,Beiing

102413，China；3．DepartmentofSurgery,TangxianPeople’SHospital，Hebei，Tangxian067203，China)

Correspondingauthor：GAOHong—bo，E．mail：gaohongbo0007@163．com

[Abstract]ObjectiveDiscussionTcm—MDPwholebodybonescanandserumprostate—specificantigen(PSA)

clinicalvalueofdiagnosisofprostatecancerwithbonemetastasis．MethodIn60casesofclinicallydiagnosed

prostatecancerpatientsunderwentwholebodyboneimagingandSCFIlmPSAdetermination．andthebonemetastasis

nadPSAlevelsbycorrelationanalysis．ResuItProsattecancerpatientswithbonemetasatsisratewas72．5％．There

iSasignificnatdifferencebetweenhteleve1ofPSAprostatecancerbonemetastasisgroupnadnonbonemetastasis

group(尸0．05)．Alongwihthteboneimaginggradingnicreased，thelevelofserumPSAincreasedrgadually,and

thecorrelationbewteen．PSA20ng／m1inpatientswithbonemetastasisratewas90．7％．andPSA≤20ng／m1．hte

nicidencerateof35-3％prostatecancerbonemeatstasis．Conclusion”Tcm-MDPwholebodyboneimagingcombnied

wihtserumPSAtesthasimportantguidingsingificanceforhte