Cintirorgon-sodium-LYC-55716-sodium-生命科学试剂-MCE.pdf

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Cintirorgonsodium

Cat.No.:HY-104037A

CASNo.:2055538-47-9

Synonyms:LYC-55716sodium

分⼦式:C₂₇H₂₂F₆NNaO₆S

分⼦量:625.51

作⽤靶点:ROR

作⽤通路:MetabolicEnzyme/Protease;VitaminDRelated/Nuclear

Receptor

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Cintirorgonsodium是⼀种⾸创的、选择性的，具有⼝服活性的RORγ激动剂。Cintirorgonsodium调节

RORγ表达的T淋巴细胞免疫细胞的基因表达，增强效应⼦功能，降低免疫抑制，降低肿瘤⽣长，提⾼⽣存率

[1][2]。

客户使⽤本产品发表的科研⽂献

•PharmacolRes.2021Jul30;105793.

•Diabetes.2023Aug8;db220605.

•EurJMedChem.2021,113585.

•AntiviralRes.2023Dec4:105769.

•Heliyon.2023Jun28.

Seemorecustomervalidationsonwww.MedChemE

REFERENCES

[1].LyceraAnnouncesInitiationofPhase1/2aStudyARGONofImmuno-OncologyCandidateLYC-55716inPatientswithAdvancedSolid

Tumors.Jan04,2017.

McePdfHeight

1/1MasterofBioactiveMolecules—