肺癌的非手术治疗进展.ppt

化疗与放疗的新联合的三种形式非常规放疗与化疗的联合：加速超分割与化疗的联合适形放疗与化疗的联合新一代化疗药物与放疗的联合谢谢大家！新的研究热点肺癌放射治疗的有关进展单击此处添加正文。常规分割放疗的弊病单击此处添加正文。肿瘤细胞----效应正常组织----损伤放射剂量肺癌放射治疗的有关进展?适行放疗的理论基础--改善放射物理剂量的分布

肿瘤组织的照射剂量↑

正常组织的照射剂量↓适行放疗方法束流适行放疗生物适行放疗三维适行放疗肺癌放射治疗的有关进展?非常规分割放疗的理论基础---

调整放疗的时间—剂量—分割因素提高正常组织的放射耐受量

增加肿瘤的放射生物效应?中国人民解放军总医院*军医进修学院中国人民解放军总医院*军医进修学院中国人民解放军总医院*军医进修学院中国人民解放军总医院*军医进修学院**Therearemajordifferencesintheincidenceandmortalityrateforlungcancerinmalesandfemales.1Thedifferencesbetweenmalesandfemales,canbeaccountedforbytrendsintobaccosmoking,whichcausesupto90%ofalllungcancer.2Althoughtheprevalenceofcurrentcigaretteusehasgenerallydecreasedovermorethan30years,thepatternofdeclinehasvariedbysexandrace.Arapidincreaseincigarettesmokinginthefirsthalfofthiscenturyoccurredfirstamongmenandthenagenerationlateramongwomen.Since1965,smokingprevalencehasdeclined,morerapidlyamongmalesthanamongfemales.Accordingly,malelungcancerincidenceanddeathratespeakedin1984and1990respectivelyandarenowdeclining,whereas,thisisnotobservedinwomen.Currenttrendsintobaccosmoking,includingincreasedadolescentsmokingduringthe1990s,mayworsenthefutureoccurrenceoflungcancer.21. RiesLAG,etal(eds).SEERCancerStatisticsReview,1973-1996,NationalCancerInstitute,Bethesda,MD, 1999.2. WingoPA,etal.JNatlCancerInst1999;91:675-690.*****肺癌的非手术治疗进展

全球肺癌流行态势发病率增长：男51.7%女83.3%调整死亡率：男31.42/10万女9.53/10万Lungcancer-USincidenceandmortalityrates(1973-1996)1050100Incidence-malesMortality-malesIncidence-femalesMortality-femalesRateper

100,000

people

(logscale)19747678808284868890929496Yearofdiagnosis/deathRiesetal1999我国流行病学情况---缺乏可靠的资料发病率：男38.46/10万女15.70/10