《医学遗传学》第四章人类染色体与染色体病.ppt

《医学遗传学》第四章人类染色体与染色体病.ppt

  1. 1、本文档共10页,可阅读全部内容。
  2. 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
  3. 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载
  4. 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多

NumericalAbnormalityBefoundmorecommonlythanEuploid(整倍体)ACB亚二倍体:lessthanthenormal2nnumberofchromosomes超二倍体:morethanthenormal2nnumberofchromosomes非整倍体NumericalAbnormality非整倍体单体型:isthepresenceofonlyonecopyofanychromosomeLossofautosomesisnottoleratedTurnersyndrome:45,X亚二倍体BefoundmorecommonlythanMonosomyTrisomyofsexchromosomeismorecommonly超二倍体三体型:isthepresenceofonlythreecopyofanychromosomeNumericalAbnormality非整倍体NumericalAbnormalityMeiotic(减数分裂)non-disjunction单击此处添加小标题Mitotic(有丝分裂)non-disjunction单击此处添加小标题Chromosomenon-disjunction单击此处添加小标题MechanismofAneuploid(非整倍体)单击此处添加小标题Meiosisinanimals.MeioticNon-DisjunctionMeioticnon-disjunctionarisesfromfailureofpairedhomologouschromosomesorsisterchromatidtodisjoinatmeioticanaphase.MeioticNon-Disjunction2NNN+1N-12N+12N+12N-12N-1N+1N+1N-1N-12N2N2N+12N-12NNNNNN-1N+1MeioticNon-DisjunctionPrimarynon-disjunction单击此处添加小标题Primarynon-disjunctionisthefailureofchromosomesorsisterchromatidtoseparateinmeiosis.Thegametethushastwocopiesofachromosome.Fertilizationaddsanothercopytogiveatotalof3copies.单击此处添加小标题Secondarynon-disjunction单击此处添加小标题Trisomyoffspringarisefromsegregationatmeiosisofanalready-trisomyparent.单击此处添加小标题MeioticNon-Disjunction2N+1N2N2N2N+12N+1NN+1NNN+1N+1NumericalAbnormalityMitoticnon-disjunction添加标题MechanismofAneuploid添加标题Meioticnon-disjunction添加标题Chromosomenon-disjunction添加标题01020304Mitosisinanimalcells.MitoticNon-DisjunctionMitoticnon-disjunctionarisesfromfailureofsisterchromatidstodisjoinatmitoticanaphase.2N2N2N2N2N2N-12N+12N2N-12N+147/45Mosaic46/47/45MosaicNumericalAbnormality添加标题Meioticnon-disjunction添加标题Mitoticnon-disjunction添加标题Chromosomeloss添加标题MechanismofAneuploid添加标题Chromosomenon-disjunctionChromosomeLoss01添加标题Thecausalitywhereach

文档评论(0)

wuyoujun92 + 关注
实名认证
内容提供者

该用户很懒,什么也没介绍

1亿VIP精品文档

相关文档