APL180-TFA-L-4F-TFA-生命科学试剂-MCE.pdf

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

APL180TFA

Cat.No.:HY-P6365

Synonyms:L-4FTFA

分⼦式:C₁₁₄H₁₅₆N₂₄O₂₈.xC₂HF₃O₂

Sequence:Ac-Asp-Trp-Phe-Lys-Ala-Phe-Tyr-Asp-Lys-Val-Ala-Glu-Lys-Ph

e-Lys-Glu-Ala-Phe-NH2

SequenceShortening:Ac-DWFKAFYDKVAEKFKEAF-NH2

作⽤靶点:Apolipoprotein

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Sealedstorage,awayfrommoisture

Powder-80°C2years

-20°C1year

Insolvent-80°C6months

-20°C1month

溶解性数据

体外实验DMSO:100mg/mL(Needultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造

成的产品失效。储备液的保存⽅式和期限：-80°C,6months;-20°C,1month(sealedstorage,awayfrom

moisture)。-80°C储存时，请在6个⽉内使⽤，-20°C储存时，请在1个⽉内使⽤。

BIOLOGICALACTIVITY

⽣物活性APL180TFA(L-4F)是⼀种载脂蛋⽩A-I模拟肽，可增强⾼密度脂蛋⽩(HDL)的抗炎活性。APL180可⽤于⼼⾎

管疾病的研究。

REFERENCES

[1].WatsonCE,etal.TreatmentofpatientswithcardiovasculardiseasewithL-4F,anapo-A1mimetic,didnotimproveselectbiomarkersof

HDLfunction.J