ORG-2766-生命科学试剂-MCE.pdf

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

ORG-2766

Cat.No.:HY-P2113

CASNo.:50913-82-1

分⼦式:C₄₀H₅₅N₉O₁₁S

分⼦量:869.98

Sequence:{Met(O2)}-Glu-His-Phe-{d-Lys}-Phe

SequenceShortening:{Met(O2)}-EHF-{d-Lys}-F

作⽤靶点:MelanocortinReceptor

作⽤通路:GPCR/GProtein;NeuronalSignaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性ORG-2766是⼀种促肾上腺⽪质激素ACTH4-9的类似物和神经营养肽。ORG-2766会影响动物的记忆和注意⼒

等⾏为过程，改善实验性过敏性神经炎⼤⿏的症状。ORG-2766具有神经保护的作⽤。

REFERENCES

[1].GoldmanH,etal.CerebralbloodflowaftertreatmentwithORG-2766,apotentanalogofACTH4--9.PharmacolBiochemBehav.1979

Jun;10(6):883-7.

[2].DuckersHJ,etal.TheneurotrophicanalogueofACTH(4-9),Org2766,protectsagainstexperimentalallergicneuritis.Brain.1993

Oct;116(Pt5):1059-75.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech