人体结构与功能 17-Neuromuscular Junction Signal Transmission and Molecular Mechanism of Muscle Contraction学习资料.ppt

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人体结构与功能 17-Neuromuscular Junction Signal Transmission and Molecular Mechanism of Muscle Contraction学习资料.ppt

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Chapter9MotorSystem-2SpinalReflex,DescendingPathwaysandCerebellum

ContentSpinalReflexesFunctionofBrainStemFunctionofCerebellum

ReferenceP164-180P464-470P473-475P673-684P691-707

Section1.SpinalReflexesSomaticreflexesmediatedbythespinalcordMayoccurwithouttheinvolvementofhigherbraincentersWasfacilitatedorinhibitedbybrainForexampleStretchreflexDeeptendonreflexCrossedextensorreflexSuperficialreflex

PartIStretchReflex

1AnatomyofMuscleSpindle3-10intrafusalmusclefibersdetectchangeinthelengthofthemuscle--stretchreceptorsthatreportthestretchingofthemuscletothespine.Thecentralregionandperipheralregionoftheintrafusalfibers

AnatomyofMuscleSpindleIntrafusalfibersarewrappedbytwotypesofafferentendingsPrimarysensoryendingsTypeIafibersInnervatethecenterofthespindleSecondarysensoryendingsTypeIIfibersAssociatedwiththeendsofthenuclearchainfiber

ComponentsofmusclespindleStaticintrafusalfibersDynamicintrafusalfiberAfferentaxonsIaIIStaticintrafusalfibersPrimaryendingSecondaryending}}NuclearBagFiberNuclearChainFiber

AnatomyofMuscleSpindlePrimarysensoryendingsTypeIafibersStimulatedbyboththerateandamountofstretch(dynamicresponse)

AnatomyofMuscleSpindleSecondarysensoryendingsTypeIIfibersstimulatedonlybydegreeofstretch(staticresponse)

AnatomyofMuscleSpindleThecontractileregionoftheintrafusalmusclefibersarelimitedtotheirendsonlytheseareascontainactinandmyosinfilamentsareinnervatedbygamma(?)efferentfibers

2.Musclestretchreflex

MusclestretchreflexDefinition:Wheneveramuscleisstretched,excitationofthespindlescausesreflexivecontractionofthesamemusclefromwhichthesignaloriginatedandalsoofcloselyalliedsynergisticmuscle.Thebasiccircuit:SpindleIaorIInervefiberdorsalrootofthespinalcordsynapseswithanteriormotorneurons?-motorN.F.