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CGP35348(Standard)

Cat.No.:HY-103530R

CASNo.:123690-79-9

分⼦式:C₈H₂₀NO₄P

分⼦量:225.22

作⽤靶点:GABAReceptor

作⽤通路:MembraneTransporter/IonChannel;NeuronalSignaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性CGP35348(Standard)是CGP35348的分析标准品。本产品⽤于研究及分析应⽤。CGP35348是⼀种选择性、

可透过⾎脑屏障的GABAB受体拮抗剂，EC50为34μM。CGP35348仅显⽰对GABAB受体的亲和⼒[1]。

CGP35348可⽤于研究⽩化新⽣⼩⿏脑损伤后的神经肌⾁协调和空间学习[2]。

REFERENCES

[1].HROlpe,etal.CGP35348:acentrallyactiveblockerofGABABreceptors.CGP35348:acentrallyactiveblockerofGABABreceptors

[2].QGillani,etal.CGP35348,GABABreceptorantagonist,hasapotentialtoimproveneuromuscularcoordinationandspatiallearningin

albinomousefollowingneonatalbraindamage.BiomedResInt.2014;2014:295215.

[3].APuigcerver,etal.EffectsoftheGABABantagonistCGP35348onsleep-wakestates,behaviour,andspike-wavedischargesinold

rats.BrainResBull.1996;40(3):157-62.

McePdfHeight

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