基于网络药理学和分子对接研究芍药苷抗帕金森病作用机制.pdf

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研究论文

基于网络药理学和分子对接研究芍药苷抗帕金森病作用机制

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材料与方法··························································································9

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中文摘要

基于网络药理学和分子对接研究芍药苷抗帕金森病作用机制

摘要

帕金森病（Parkinsonsdisease，PD）是一种复杂的多因子神经退

行性疾病，是继阿尔茨海默病之后的第二大神经退行性疾病。目前，

治疗PD的药物主要包括左旋多巴制剂、多巴胺受体激动剂、单胺氧化

酶B抑制剂、甲基转移酶抑制剂和其他如抗胆碱能类药物等，疾病后

期需要多药联合。尽管这些药物能够减轻患者症状，但需要长期服药，

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