安徽地区283例慢性过敏性皮肤病斑贴试验结果分析.pdfVIP

安徽医药AnhuiMedicalandPharmaceuticalJournal2013Mar；17(3)·447·

安徽地区283例慢性过敏性皮肤病斑贴试验结果分析

刘蔚，姚秀华，张兰芳，胡白

(安徽医科大学附属省立医院皮肤科，安徽合肥230001)

摘要：目的探讨慢性过敏性皮肤病患者常见的致敏原及其特点，为其防治提供依据。方法应用“瑞敏牌”斑贴试剂盒检测

283例慢性过敏性皮肤病患者，对试验数据进行统计学分析和比较。结果283例患者中有158例对2O种致敏原中的1种或2

种以上呈现阳性反应，总阳性率为55．83％。阳性率高的前5位过敏原依次为：硫酸镍(20．14％)、甲醛(14．49％)、氯化钻

(13．43％)、cl+Me一异噻唑(12．O1％)、芳香混合物(10．95％)等。皮损位于躯干四肢者对甲醛阳性率最高(21．88％)，唇炎对

松香阳性率最高(10．64％)。性别、年龄间斑贴试验阳性率无明显差异。结论斑贴试验寻找慢性过敏性疾病致敏原简单可

靠；不同部位皮损和不同病种的常见致敏原不同。

关键词：斑贴试验；皮肤病；致敏原

Patchtestresultsanalysisof283casesofchronic

dermatitispatientsinAnhui

UUWei。YA0Xiu．hua．ZHANGLan．fang，etal

(DepartmentofDermatology，AnhuiProvincialHospitalAffiliatedtoAnhuiMedicalUniversity，Hefei，Anhui230001，China)

Abstract：ObjecfiveTodetectandanalyzethecommonallergensandthecharacterofchronicallergicdermatitis，andtoprovidetheba—

sisforpreventionandtreatmentofthedisease．Methods283diagnosedcasesofchronicallergicdermatitisweretestedwithastandrad．

izedpatchtestingtechnique(ReiMinPai)againstcontactallergens．Thetestdatawereanalyzedbystatisticalmethodsandtheresultswere

comparedwithnationalmonitoringresults．Results158caseswereallergictoatleastoneantigenin20kindsofstandardseriesanti—

gens．Thetotalpositiveratewas55．83％．Theseveralantigenswhichcausedthetop5highpositiveratewere：nickelsulphate

(20．14％)，formaldehyde(14．49％)，cobaltchloride(13．43％)，C1+Me—isothiazole(12．O1％)，aromaticcompounds(10．95％)．The

mostcommonallergencausingdemratitisoftrunkandlimbswasformaldehyde(21．88％)．Themostcommonallergencausingcheilitis

wascolophony(10．64％)．Therewasnostatisticallysignificantdifferencebetweenbothsexesandalsoamongdifferentagegroups．Con—

clusionPatchtestisareliableandsimplemethodforlookingofrallergensinchronicallergicdemratitis．Thereraedifferentallergensin

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