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HighBloodPressureCardiovascularPreventionOnlineISSN1179-1985

/10.1007/s40292-025-00710-3

REVIEWARTICLE

AorticRemodelinginPatientswithArterialHypertension:

PathophysiologicalMechanisms,TherapeuticInterventionsand

PreventiveStrategies—APositionPaperfromtheHeartand

HypertensionWorkingGroupoftheItalianSocietyofHypertension

111213,4,5

Costantino

Mancusi

·Christian

Basile

·Ilaria

Fucile

·Carlo

Palombo

·Maria

Lembo

·Giacomo

Buso

·

3,4,56789,10

Claudia

Agabiti-Rosei

·Valeria

Visco

·Antonietta

Gigante

·Giuliano

Tocci

·Alessandro

Maloberti

·

Chiara

Tognola9,10

·Giacomo

Pucci11,12

·Rosa

Curcio13

·Sebastiano

Cicco14

·Federica

Piani15

·

MarialuisaSveva

Marozzi14

·Alberto

Milan16,17

·Dario

Leone16,17

·Chiara

Cogliati18

·Riccardo

Schiavon19

·

2061213,4,5,6

Massimo

Salvetti

·Michele

Ciccarelli

·Nicola

De

Luca

·Massimo

Volpe

·MariaLorenza

Muiesan

Received:25November2024/Accepted:18February2025

©TheAuthor(s)2025

Abstract

Inpatientwitharterialhypertensionthewholeaortaisexposedtoincreasedwallstressduetopressureoverload.Different

bloodpressure(BP)componentshavebeenreportedasmaindeterminantofaorticremodelling.Inparticularincreased

diastolicBPhasbeenassociatedwithaorticdilatationacrossallitssegmentswithsmallerincreaseinaorticrootand

ascendingaortarelatedt