2024+国际共识声明：经皮冠状动脉介入治疗中血小板功能和基因检测（更新版）.pdfVIP

JACC:CARDIOVASCULARINTERVENTIONSVOL.17,NO.22,2024

ª2024BYTHEAMERICANCOLLEGEOFCARDIOLOGYFOUNDATION

PUBLISHEDBYELSEVIER

STATE-OF-THE-ARTREVIEW

InternationalConsensusStatementon

PlateletFunctionandGeneticTestingin

PercutaneousCoronaryIntervention

2024Update

DominickJ.Angiolillo,MD,PHD,aMattiaGalli,MD,PHD,b,cDimitriosAlexopoulos,MD,PHD,d,e

DanielAradi,MD,PHD,e,fDeepakL.Bhatt,MD,MPH,MBA,gLaurentBonello,MD,PHD,h

DavideCapodanno,MD,PHD,iLarisaH.Cavallari,PHARMD,jJean-PhilippeCollet,MD,PHD,k

ThomasCuisset,MD,PHD,lJoseLuisFerreiro,MD,PHD,mFrancescoFranchi,MD,aTobiasGeisler,MD,n

C.MichaelGibson,MD,oDianaA.Gorog,MD,PHD,p,qPaulA.Gurbel,MD,PHD,rYoung-HoonJeong,MD,PHD,s,t

RossellaMarcucci,MD,PHD,uJolantaM.Siller-Matula,MD,PHD,vRoxanaMehran,MD,w

Franz-JosefNeumann,MD,PHD,xNaveenL.Pereira,MD,y,zKonstantinosD.Rizas,MD,aa,bbFabianaRollini,MD,a

DerekY.F.So,MD,ccGreggW.Stone,MD,ddRobertF.Storey,MD,eeUdayaS.Tantry,MD,PHD,r

JurrienTenBerg,MD,PHD,ff,gg,hhDietmarTrenk,MD,PHD,iiMarcoValgimigli,MD,PHD,jj,kk,llRonWaksman,MD,mm

DirkSibbing,MD,MHBAaa,nn

ABSTRACT

CurrentevidenceindicatesthatdualantiplatelettherapywithaspirinplusaP2Y12inhibitorisessentialfortheprevention

ofthromboticeventsafterpercutaneouscoronaryinterventions.However,dualantiplatelettherapyisassociatedwith

increasedbleedingwhichmayoutweighthebenefits.Thishassetthefoundationsforcustomizingantiplatelettreat-

mentstotheindividualpatient.However,bleedingandischemicrisksareoftenpresentinthesamepatient,makingit

difficulttoachievethisbalance.ThefactthatoralP2Y12inhibit