1-4-4-4-5-5-Tetramethyl-1-3-2-dioxaborolan-2-yl-phenyl-piperazine-生命科学试剂-MCE.pdfVIP

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1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine

Cat.No.:HY-W118465

CASNo.:912369-50-7

分⼦式:C₁₆H₂₅BN₂O₂

分⼦量:288.2

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:4°C,protectfromlight

*Insolvent:-80°C,6months;-20°C,1month(protectfrom

light)

BIOLOGICALACTIVITY

⽣物活性1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine是⼀种PROTAClinker，可⽤于合成

PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE52ubiquitinligaseand

theotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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