4-tert-Butyldimethylsilyl-oxy-butan-1-ol-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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4-((tert-Butyldimethylsilyl)oxy)butan-1-ol

Cat.No.:HY-W012471

CASNo.:87184-99-4

分⼦式:C₁₀H₂₄O₂Si

分⼦量:204.39

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Pureform-20°C3years

4°C2years

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性4-((tert-Butyldimethylsilyl)oxy)butan-1-ol是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE323ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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