4-Carboxymethyl-phenylboronic-acid-pinacol-ester-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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4-(Carboxymethyl)phenylboronicacidpinacolester

Cat.No.:HY-W000969

CASNo.:797755-07-8

分⼦式:C₁₄H₁₉BO₄

分⼦量:262.11

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Storeatroomtemperature3years

*Insolvent:-80°C,6months;-20°C,1month(Storeatroom

temperature3years)

BIOLOGICALACTIVITY

⽣物活性4-(Carboxymethyl)phenylboronicacidpinacolester是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE353ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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