4-Chloromethyl-phenylacetic-Acid-生命科学试剂-MCE.pdfVIP

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4-(Chloromethyl)phenylaceticAcid

Cat.No.:HY-W613504

CASNo.:56066-91-2

分⼦式:C₉H₉ClO₂

分⼦量:184.62

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性4-(Chloromethyl)phenylaceticAcid是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE354ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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