4-Methoxycarbonyl-bicyclo-2-2-2-octane-1-carboxylic-acid-生命科学试剂-MCE.pdfVIP

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4-(Methoxycarbonyl)bicyclo[2.2.2]octane-1-carboxylicacid

Cat.No.:HY-W001270

CASNo.:18720-35-9

分⼦式:C₁₁H₁₆O₄

分⼦量:212.25

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Storeatroomtemperature3years

*Insolvent:-80°C,6months;-20°C,1month(Storeatroom

temperature3years)

BIOLOGICALACTIVITY

⽣物活性4-(Methoxycarbonyl)bicyclo[2.2.2]octane-1-carboxylicacid是⼀种PROTAClinker，可⽤于合成PROTAC分

⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE355ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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