4-tert-Butyldimethylsilyl-oxy-butan-1-amine-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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4-((tert-Butyldimethylsilyl)oxy)butan-1-amine

Cat.No.:HY-W440597

CASNo.:245660-15-5

分⼦式:C₁₀H₂₅NOSi

分⼦量:203.4

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:4°C,protectfromlight

*Insolvent:-80°C,6months;-20°C,1month(protectfrom

light)

BIOLOGICALACTIVITY

⽣物活性4-((tert-Butyldimethylsilyl)oxy)butan-1-amine是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE322ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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