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Amesergide

Cat.No.:HY-105277

CASNo.:121588-75-8

分⼦式:C₂₅H₃₅N₃O

分⼦量:393.56

作⽤靶点:5-HTReceptor

作⽤通路:GPCR/GProtein;NeuronalSignaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Amesergide是⼀种⾎清素(5-HT1C/2)拮抗剂。Amesergide可导致母畜后代体重增长减少。Amesergide可

⽤于抑郁症的研究[1][2]。

REFERENCES

[1].Seyler,D.E.,etal.,(1993).Effectsoftheserotoninantagonistamesergideonreproductioninfemalerats.Reproductivetoxicology

(Elmsford,N.Y.),7(6),607-612.

[2].Kelich,S.L.,etal.,(1995).DevelopmentaltoxicityofamesergideadministeredbygavagetoCDratsandNewZealandwhite

rabbits.Fundamentalandappliedtoxicology:officialjournaloftheSocietyofToxicology,27(2),247-251.

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