南开大学《分子生物学》2021-2022学年期末试卷.docxVIP

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南开大学《分子生物学》2021-2022学年期末试卷.docx

南开大学考试试卷

2021——2022学年第1学期

课程名称:

分子生物学

考试时间

120分钟

专业

年级

学号

姓名

题号

总得分

得分

评卷人签字

复核人签字

一、填空题(每空0.5分,共10分)

得分

1、TheenzymesneededinthebacterialDNAreplicationaretopoisomerase,helicase,_____________,DNApolymeraseand______________.

2、Therearefivefamiliesofhistones:________,________,________and________,knownasthecorehistones,andH1.

3、TheholoenzymeofE.coliRNApolymeraseis_______________,thecoreenzymeismadeupof_______________,whilethe___________factorhastheabilitytorecognizespecificbindingsites

.

4、Therearetwokindsofmutagens,oneisphysicalmutagens,suchas_____________,theotherischemicalmutagens,suchas_____________.

5、Thetwo-dimensionalstructureoftRNAis.Andthethree-dimensionalstructureoftRNAis.

6、wassuggsetedbyCricktoexplaintheredundancyofthegeneticcode.

7、Thestartcodonis.Therearethreestopcodons:,,

.

siteiswherethe

8、

siteiswhereincomingaminoacyl-tRNAmoleculesbind,and

growingpolypeptidechainisusuallyfound.

二、名词解释(每小题2分,共30分)

得分

1、semi-conservativereplication

2、Tm

3、asymmetryoftranscription

4、Transition

5、Exon

6、Transposon

7、Operon

8、Synonymouscodon

9、Ribosome

10、Shine-Dalgarnosequence

11、housekeepinggene

12、Ribozyme

13、Chaperon

14、DNAclone

15、Phage

三、单项选择题(每小题1分,共15分)

得分

()1、DNAreplicationineukaryotes:

A.usuallystartsatthesameplaceeverytime

B.onlyinvolve2differentDNApolymerases

C.isfasterthaninbacterialDNAreplication

D.alloftheabovearefalse

()2、Whichofthefollowingaretruestatementsregardingtelomeres:

A.theystabilizelinearchromosomes

B.theyconsistofashortrepeatingsequence

C.theyarelocatedatthechromosomeends

D.alloftheabovearetrue

()3、Mismatchesproducedfromreplicationerrorsarefirstrecognizedby________forthe

purposesofrepair.

A.MutHB.MutMandMutL

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