疫苗全价值评估：针对改良流感疫苗的分析.pptxVIP

Improvedinfluenzavaccines

Fullvaluevaccineassessment

Contents

Acknowledgementsvii

Abbreviationsviii

Executivesummaryix

1.WHO’sfullvalueofimprovedseasonalinfluenzavaccines1

1.1WHO’scallforimprovedseasonalinfluenzavaccines1

1.2Definitionandpurposeofafullvalueofvaccineassessment1

1.3WHOpreferredproductcharacteristicsfornext-generationinfluenzavaccines2

1.4RelationshipbetweentheFVIVAandthePPCs4

1.5MethodologydevelopmentfortheFVIVA4

2.Theglobalpublichealthneedforimprovedseasonalinfluenzavaccines6

2.1Diseasedescription6

2.2Currentmethodsofsurveillance,diagnosis,preventionandtreatment7

2.3Keygapsinknowledgeorresearchevidence8

3.Targetaudiencesandstakeholderengagement9

3.1TargetaudiencesfortheFVIVA9

3.2Overviewoftheinfluenzastakeholderecosystem9

3.3StakeholderinvolvementinFVIVA11

4.Developmentofimprovedseasonalinfluenzavaccinesand

assessmentofthepipeline12

4.1Biologyoftheinfluenzavaccine