CYP51-IN-31-生命科学试剂-MCE.pdfVIP

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CYP51-IN-31

Cat.No.:HY-179483

分⼦式:C₃₅H₃₆ClF₂N₇O₂

分⼦量:660.16

作⽤靶点:CytochromeP450;Fungal

作⽤通路:MetabolicEnzyme/Protease;Anti-infection

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性CYP51-IN-31(compoundT24)是⼀种选择性CYP51抑制剂，具有强效⼴谱抗真菌(antifungal)活性，包括对

耐药真菌菌株的活性。CYP51-IN-31对近平滑念珠菌具有杀真菌活性，具有抗⽣物膜活性，并能抑制真菌形态

转变。CYP51-IN-31可⽤于感染研究[1]。

REFERENCES

[1].ZhangJ,etal.Design,synthesis,andactivityevaluationofnoveltetrazole-basedCYP51inhibitors.BioorgChem.2025

Nov;166:109132.

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