DCAI-生命科学试剂-MCE.pdfVIP

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DCAI

Cat.No.:HY-118692

CASNo.:299165-92-7

分⼦式:C₁₁H₁₂Cl₂N₂

分⼦量:243.13

作⽤靶点:Ras

作⽤通路:GPCR/GProtein;MAPK/ERKPathway

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性DCAI是Ras蛋⽩结合剂。DCAI能够抑制由SOS介导的Ras激活和核苷酸交换。DCAI可⽤于与Ras突变相关

的癌症研究[1]。

REFERENCES

[1].MaurerT,etal.Small-moleculeligandsbindtoadistinctpocketinRasandinhibitSOS-mediatednucleotideexchangeactivity.ProcNatl

AcadSciUSA.2012Apr3;109(14):5299-304.

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