F-15845-hydrobromide-生命科学试剂-MCE.pdfVIP

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

F-15845hydrobromide

Cat.No.:HY-19463

CASNo.:866760-23-8

分⼦式:C₂₀H₂₆BrNO₂S₂

分⼦量:456.46

作⽤靶点:SodiumChannel

作⽤通路:MembraneTransporter/IonChannel

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性F15845hydrobromide是⼀种⾼效的持久性钠电流阻滞剂。F15845hydrobromide也是⼀种⼼脏保护剂

，具有抗缺⾎活性，可在⼼肌梗塞后发挥短期和长期⼼脏保护作⽤。F15845hydrobromide可⽤于⼼肌功能

障碍的研究。

REFERENCES

[1].BrunoVié,etal.3-(R)-[3-(2-methoxyphenylthio-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepinebromhydrate(F15845)

preventsischemia-inducedheartremodelingbyreductionoftheintracellularNa+overload.JPharmacolExpTher.2009Sep;330(3):696-

703.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师