Rho-Kinase-IN-1-Standard-生命科学试剂-MCE.pdfVIP

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Rho-Kinase-IN-1(Standard)

Cat.No.:HY-100270R

CASNo.:1035094-83-7

分⼦式:C₂₀H₂₄N₄S

分⼦量:352.5

作⽤靶点:ROCK;ReferenceStandards

作⽤通路:CellCycle/DNADamage;Cytoskeleton;StemCell/Wnt;TGF-

beta/Smad;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Rho-Kinase-IN-1(Standard)是Rho-Kinase-IN-1(HY-100270)的分析标准品。本产品⽤于研究及分析应⽤。

Rho-Kinase-IN-1是⼀种Rho激酶(ROCK)抑制剂(ROCK1，ROCK2的Ki分别是30.5，3.9nM)。详细信息请参

考专利US20090325960A1，化合物1.008[1]。

IC50TargetKi:30.5nM(ROCK1),3.9nM(ROCK2)[1]

REFERENCES

[1].Fulcher,EmileeH,etal.MethodforthetreatmentandpreventionoftheinflammatorydiseasesusingRhokinaseinhibitingcompounds.

US20090325960A1.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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