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(±)-E-Homocamptothecin

Cat.No.:HY-131540

CASNo.:186668-40-6

Synonyms:BN80245

分⼦式:C₂₁H₁₈N₂O₄

分⼦量:362.38

作⽤靶点:Topoisomerase

作⽤通路:CellCycle/DNADamage

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性(±)-E-Homocamptothecin(BN80245)是⼀种拓扑异构酶I(topoisomeraseI)抑制剂。(±)-E-

Homocamptothecin可⽤于癌症研究[1]。

IC50TargetTopoisomeraseI

REFERENCES

[1].LavergneO,etal.BN80245:anE-ringmodifiedcamptothecinwithpotentantiproliferativeandtopoisomeraseIinhibitoryactivities[J].

BioorganicMedicinalChemistryLetters,1997,7(17):2235-2238.

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1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师