RIPA-56-Standard-生命科学试剂-MCE.pdfVIP

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RIPA-56(Standard)

Cat.No.:HY-101032R

CASNo.:1956370-21-0

分⼦式:C₁₃H₁₉NO₂

分⼦量:221.3

作⽤靶点:RIPkinase;ReferenceStandards

作⽤通路:Apoptosis;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性RIPA-56(Standard)是RIPA-56(HY-101032)的分析标准品。本产品⽤于研究及分析应⽤。RIPA-56是⼀种⾼

效选择和代谢稳定的受体相互作⽤蛋⽩1(RIP1)抑制剂，IC50为13nM。RIPA-56可⽤于研究全⾝炎症反应综

合征[1]。

IC50TargetIC50:13nM(RIP1)[1]

REFERENCES

[1].RenY,etal.DiscoveryofaHighlyPotent,Selective,andMetabolicallyStableInhibitorofReceptor-InteractingProtein1(RIP1)forthe

TreatmentofSystemicInflammatoryResponseSyndrome.JMedChem.2017Feb9;60(3):972-986.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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