Mal-Cyclobutane-1-1-dicarboxamide-Cit-PAB-MMAE-生命科学试剂-MCE.pdfVIP

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Mal-Cyclobutane-1,1-dicarboxamide-Cit-PAB-MMAE

Cat.No.:HY-148227

CASNo.:2226490-67-9

分⼦式:C₆₈H₁₀₃N₁₁O₁₅

分⼦量:1314.61

作⽤靶点:Drug-LinkerConjugatesforADC

作⽤通路:Antibody-drugConjugate/ADCRelated

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Mal-Cyclobutane-1,1-dicarboxamide-Cit-PAB-MMAE(Compound31)是⼀种ADC药物-连接⼦偶联物(Drug-

LinkerConjugatesforADC)。Mal-Cyclobutane-1,1-dicarboxamide-Cit-PAB-MMAE由MMAE(HY-15162)和

Mal-Cyclobutane-1,1-dicarboxamide-Cit-PABcarbonicacid(HY-171663)组成[1]。

REFERENCES

[1].WeiB,etal.DiscoveryofPeptidomimeticAntibody-DrugConjugateLinkerswithEnhancedProteaseSpecificity.JMedChem.2018Feb

8;61(3):989-1000.

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