tert-Butyl-2-7-diazaspiro-3-5-nonane-7-carboxylate-hydrochloride-生命科学试剂-MCE.pdfVIP

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tert-Butyl-2-7-diazaspiro-3-5-nonane-7-carboxylate-hydrochloride-生命科学试剂-MCE.pdf

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylatehydrochloride

Cat.No.:HY-30747

CASNo.:1023301-84-9

分⼦式:C₁₂H₂₃ClN₂O₂

分⼦量:262.78

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Storeatroomtemperature,keepdryandcool

*Insolvent:-80°C,6months;-20°C,1month(Storeatroom

temperature,keepdryandcool)

BIOLOGICALACTIVITY

⽣物活性tert-Butyl2,7-diazaspiro[3.5]nonane-7-carboxylatehydrochloride是⼀种PROTAClinker,可⽤于合成

PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE925ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

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