LCB-2122-生命科学试剂-MCE.docxVIP

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

LCB-2122

Cat.No.:HY-180575

CASNo.:2210298-14-7

分?式:C??H??ClN?O?P

分?量:465.83

作?靶点:NucleosideAntimetabolite/Analog;Apoptosis;AMPK;Acetyl-

CoACarboxylase

作?通路:CellCycle/DNADamage;Apoptosis;Epigenetics;

PI3K/Akt/mTOR;MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性LCB-2122

?种腺苷样核苷类似物，具有C2-?体异构全碳季碳中?。LCB-2122能够抑制Doxorubicin(HY-

15142A)诱导的?肌凋亡(apoptosis)，其IC50值为0.5μM，并且可以抑制Imatinib(HY-15463)诱导的