新生儿呼吸窘迫综合症(Neonatal-Respiratory-Distress-Syndrome).pptVIP

NeonatalRespiratoryDistressSyndrome(NRDS)

Hyalinemembranedisease(HMD)MostcommoncauseofrespiratoryfailureinthefirstdaysintheprematureinfantsReasonissurfactantinsufficientinlungswhichleadtobreathingfailureandneedtheassistantventilationOccurringin1~2%ofnewborninfants,increasesbysmallerGA:50%ofGA28w,lessthan30%of32~36w)

SurfactantKeepthelungalveoliopenStartsynthesisinGA24~28wbylungtypeIIalveolarcellsIncreasein28~35w,butproduceadequateamountsafter35wdoubleinalveolarwithin24hafterbirth,toadultlevelafter