核磁医学Pharmaron PHN603医师培训课件PPT Lecture 06.pdfVIP

Practical

Organic

Chemistry

Lecture

3

Flash

Chromatography

•Be

sure

to

run

good

analytical

TLC

•The

key

to

the

effectiveness

of

flash

chromatography

is

that

a

comparatively

fine

silica

powder

is

used,

with

a

relatively

narrow

particle

range

(e.g.

Merck

C60,40-63pn-1,

type

9385

or

May

and

Baker

Sorbsil

C60

(40-60um)

•Silicadustisverytoxicifinhaled,youshouldthereforetake

precautionstoavoidbreathingitinandalwayshandleitinafume

cupboard.Largevolumesofsolventarealsousedfor

chroma