综合治疗中脑胶质瘤的假性进展(附15例报告).pdfVIP

·论 著· 综合治疗中脑胶质瘤的假性进展(附15例报止) 李刚’ 牟永告’ 魏大年’ 张湘衡’ 吴秋良” 谢传淼”’ 陈忠平“ 【摘要J 2006年1月至2008年7月，在中山大学肿瘤防治中心接受化疗的93例胶质瘤患者病例，对psPD患者资料回顾分 CriteriainSolid Evaluation 析。参照实体瘤疗效判定标准(Response resonance MT阴性(即一或±)者。结论psPD是脑胶质瘤综合治疗过程中并不罕见的影像学现象。我们在遇到疑似psPD 的患者时，对治疗方案是否更换要慎重，而密切的动态观察是最重要的鉴别psPD的方式。 【关键词l胶质瘤假性进展化疗 【中图分类号】R739．41 【文献标识码】A of of15Cases．12 PseudoprogressionGlioma：report Gang，MOUYonggao，WEIDanian，ZHANGXiangheng， WU Chuanmiao，CHEN CancerReseawhinSouthern Qiuliang，XIE Zhongping．State研LaboratoryforChina，Department Yat-senUniversi— ofNeurosurgery／neuro-oncology；Department矿Pathology；DepartmentofRadiology，CancerCenter，Sun ty，Guasgzhou．510060．Tel：020 To clinical of 【Abstract】Objectiveanalyze phenomenonpseudoprogression(psPD)ingliomapatients．Methods with CancerCenterofSunYat-senUni- Ninety-threepatientspathologicallydiagnosedgliomasreceivingchemotherapy，at from 2006to underwent for reviewed．All resonance versityJ帅uary July2008，were patients magnetic imaging(MRI)8Cflli assessmentof tothe andthe tothe wereassessed totheestablished responsestherapy responsestherapy according response evaluationcriteriainsolid Fifteen 93caseswereconsideredas tmnours(RECIST)．Resultscases(16．1％)of psPD．a_ occurred3 occurredwithin3monthsand5cases monthsafter caseshadtheOo· mongthem，，10 beyond radiotherapy．Nine