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The 100: A Ranking of the Most Influential Persons in History Newton, Isaac 1643 – 1727 (牛顿，艾萨克) Physicist and mathematician. Born January 4, 1643 (some sources say December 25, 1642) in Woolsthorpe, a hamlet in southwestern Lincolnshire, England. When Newton was a child, Lincolnshire was a battleground of the civil wars, in which religious dissension and political rebellion was dividing Englands population. Also of significance for his early development were circumstances within his family. He was born after the death of his father, and in his third year his mother married the rector of a neighboring parish and left her son at Woolsthorpe in the care of his grandmother. After a rudimentary education in local schools, he was sent at the age of 12 to the Kings School in Grantham, where he lived in the home of an apothecary named Clark. It was from Clarks stepdaughter that Newtons biographer William Stukeley learned many years later of the boys interest in her fathers chemical library and laboratory and of the windmill run by a live mouse, the floating lanterns, sundials, and other mechanical contrivances Newton built to amuse her. Although she married someone else and he never married, she was the one person for whom Newton seems to have had a romantic attachment. At birth Newton was heir to the modest estate which, when he came of age, he was expected to manage. But during a trial period midway in his course at Kings School, it became apparent that farming was not his metier. In 1661, at the age of 19, he entered Trinity College, Cambridge. There the questioning of long-accepted beliefs was beginning to be apparent in new attitudes toward mans environment, expressed in the attention given to mathematics and science. After receiving his bachelors degree in 1665, apparently without special distinction, Newton stayed on for his masters; but an epidemic of the plague caused the university to close. Newton was back at Woolsthorpe for 18 months in 1666 and 1667. Duri