中国幽门螺杆菌感染流行病学Meta 分析.pdfVIP

·幽门螺杆菌与胃癌· 中国幽门螺杆菌感染流行病学Meta 分析 王凯娟 王润田 【摘要】 目的 综合分析中国幽门螺杆菌（ ）流行状况。方法 采用 分析对中国 Hp Meta 1990 ～ 2002 年发表的有关 流行病学文献进行汇总、归纳和统计学分析。结果 共检索 篇文献， Hp 3 564 Hp 感染在我国分布广泛，平均感染率为 ， 岁组已达 以上， 感染呈现明显的家庭聚 58 .07 % 10 ～ 20 50 % Hp 集性。 是胃肠疾病发生的危险因素。结论 中国为 高感染率地区，家庭内传播可能是 感染 Hp Hp Hp 的主要途径。 感染与胃部疾病有关联性，开展 感染和相关疾病的防治意义重大。 Hp Hp 【关键词】 幽门螺杆菌；流行病学； 分析 Meta Meta-analysis on the epidemiology of Helicobacter pylori infection in China WANG Kai-j uan ，WANG Run- tian . Dep artment of Ep idemiology and Statistics ，School of Public Health ，Peking University ，Beij ing 100083， China 【 】 （ Abstract Objective To understand the epidemiologic features and etiology of Helicobacter pylori H . pylori）infection in China so as to provide evidence for the development of preventive measures on H . pylori infection and related diseases . Methods Meta-analysis was used to evaluate the data extracted from 1990-2002 published papers on the epidemiology of H . pylori infection in China . Results The average infection rate of H . ， pylori infection in China was 58 .07 % with 50 % in 10 to 20 year-olds . Significant intrafamilial clustering was observed. H . pylori infection was a risk factor to develop gastrointestinal disease . Conclusions H . pylori ， infections in Chinese were common and extensively distributed which might due to close contact between family