瞬时弹性成像技术中改进应变估计的匹配滤波器设计.pdfVIP

Vol. 4 No.1/ Jan.Vol. 4 No.1/ Jan. 010010 瞬时弹性成像技术中改进应变估计的 匹配滤波器设计 Match Filter design for Improved Strain Estimation in Transient Elastography 姚慧　凌涛　徐琛　李彦明　郑海荣 摘 要 用超声瞬时弹性成像技术测量组织机械特性(例如剪切波速度)有广泛的临床应用价值。很多疾病例如肝硬化、乳 腺癌可以用代表组织硬度的杨氏模量表征，该参数可以用剪切波速度直接计算出来。在超声瞬时弹性成像技术中在信噪比 很高的情况下才可以准确的计算出该参数。我们设计了一个匹配滤波器沿着时间方向和估测的偏移卷积以增加信噪比。卷 积结果表明匹配滤波器可以极大的增加图像应变质量以便更准确的计算杨氏模量。 关键词 瞬时弹性成像；应变；匹配滤波器 ABSTRACT Ultrasonic transient elastography for tissue biomechanical parameters (such as shear velocity) measurement has significant clinical applications. The Youngs modulus, which represent the tissue stiffness, is a recognized indicator of many diseases such as liver fibrosis, breast cancer, can be directly calculated from the shear velocity. In order to estimate the shear velocity accurately, transient elastography usually requires a high signal to Noise ratio (SNR) in the region of interest (ROI). We designed a match filter to convolute with the estimated displacement in the time direction to boost the SNR of the displacement for a better strain image mapping. The convoluted result shows the match filter can significantly improve the strain image quality and help getting more accurate Youngs modulus estimation. KEYWORDS　transient elastography;strain;match filter 1 Introduction lastography is an emerging medical imaging method. 2　Methodology and System Description EBiological tissues Youngs modulus or stiffness depends on its molecular compose and its corresponding e designed a real-time system to measure microstructure, and has a strong correlation with its Wtissue stiffness information based on transient biological characteristics. Transient elastography or elastography [10] .The system