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Facial contour corrections with calcium hydroxyapatite granules and fibrin sealant Maurice Mommaerts President European Association for Cranio-Maxillo-Facial Surgery Bruges, Belgium 7th Asian Pacific Craniofacial conference, Taipeh, Taiwan Issues Contour irregularities in corrective osteotomies In chin osteotomy In sagittal split osteotomy for mandibular advancement in skinny ladies Post trauma congenital defects Orbital region Temporal areas Localized midfacial deficiency in clefts and craniofacial syndromes Residual asymmetries uncorrectable with osteotomies Mandibular border lateral surface 2003-2008 caseload of 48 patients Combination Sealant Sealant Calcium hydroxylapatite Application mode 1 Application mode 2 Chin osteotomy - anterior Chin osteotomy - lateral Mandibular angle in asymmetries Mandibular angle in drag king In facial makeover Infraorbital augmentation Conclusion Your site here LOGO LOGO Hydroxyapatite Pro Osteon (Interpore Cross) Fibrin glue Tisseel/Tissucol Bone paste Human cancellous bone Pro Osteon Implant 500 Blood clot Tisseel clot Purified fibrinogen (a protein) Purified thrombin (an enzyme) derived from human blood Human blood factor XIII Aprotinin, derived from cows lungs Factor XIII strengthens blood clots by forming cross-links between strands of fibrin Aprotinin is a protein that inhibits the enzymes that break down blood clots Fibrin sealant (FS) Hemostasis Sealing Closing effect As of 2003, all fibrin sealants used are made from blood plasma taken from carefully screened donors and rigorously tested to eliminate hepatitis viruses, HIV-1, and parvovirus. Fibrin sealant (FS) A mineral Naturally occurring form of calcium apatite Ca5(PO4)3(OH 70% of bone is made up of HA Ability to integrate in bone structures support bone ingrowth, without breaking down or dissolving (i.e it is bioactive) Granules (HA) text2 anterior step 1 day postop late

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