颅底脊索瘤临床研究进展.pdfVIP

综　述 | Review 磁共振成像 2012年第3卷第5期　Chin J Magn Reson Imaging, 2012, Vol 3, No 5 颅底脊索瘤的临床研究进展 * 李梦远 综述，艾　林 审校 作者单位： [摘要]　颅底脊索瘤是一种原发低度恶性肿瘤，具有局部侵袭特性和高复发 首都医科大学附属北京天坛医院神经 率，预后较差。作者结合文献对颅底脊索瘤的流行病学、临床表现、影像学特 影像中心，北京　100050 征及组织病理学等方面进行了精要回顾，对脊索瘤的临床分型及分期、治疗原 则及生存与预后相关的因素等做了详细的综述，认为目前国内外对颅底脊索瘤 通讯作者： 的诸多方面的研究仍存在很大的分歧，需要进一步明确。 艾林，E-mail ：ailin136@ [关键词]　脊索瘤；颅底肿瘤；神经外科手术；肿瘤分期；预后 收稿日期：2011-06-27 接受日期：2012-08- 15 Recent advances in clinical of skull base chordoma 中图分类号：R445.2 ；R730.269 LI Meng-yuan, AI Lin* 文献标识码：A Imaging center of neuroradiology, Beijing Tiantan Hospital, Capital Medical DOI: 10.3969/j.issn.1674-8034.2012.05.016 University, Beijing 100050, China * Correspondence to: AI Li,E-mail: ailin136@ Received 27 June 2012; Accepted 15 Aug 2012 李梦远, 艾林. 颅底脊索瘤的临床研究 进展. 磁共振成像, 2012, 3(5): 392-396. Abstract Skull base chordoma is a rare low-grade malignant tumor. Due to its critical location, local aggressive nature, and high recurrence, skull base chordoma is still a challenge to clinicians. In this review, we summarize the epidemiology, clinical manifestations, imaging features and histopathology of skull base chordoma. Moreover, through the detailed review on this tumor’s clinical type and stage, management, and prognostic factors, we find out that many aspects of the skull base chordoma, at home and abroad, are still significant differences. Further s