IPC改善下肢皮肤灌注的效果.pdfVIP

IPC 改善下肢皮肤灌注的效果 Effect of Intermittent Pneumatic Compression on Lower Limb Skin Perfusion Shyam V. S. Rithalia, Ph.D. Mahendra Gonsalkorale, M.D.* and Jack Edwards, Ph.D. SALFORD, ENCLAND Abstract Transcutaneous oxygen (tcPO2) and carbon dioxide (tcPCO2) measurementswere used before, during, and after intermittent pneumatic compression (IPC)to assess lower limb skin perfuson in 21 healthy adult volunteers and 23 elderly patients. The temperature of the sensors was set at 44~C during calibration andmaintained throughout all tests. Resting tcPO2 was significantly lower (p 0.01)in patients than in controls. In all subjects tcPO2 decreased and tcPCO2 in-creased during compression. Patients showed a highly significant increase (p 0.001) in tcPCO2 during and after the treatment. Results of this study indicate that the symptomatic improvement, in peripheral vascular disease and wound healing following IPC, is not due to improved skin perfusion or enhancement of oxygenation and C02 removal. Introduction In recent years there has been an increasing interest in intermittent pneumatic compression (IPC) devices. They have been used successfully for the prevention of early postoperative deep vein thrombosis and the conservative treatment of lymphedema.2 More recently IPC has been prescribed for the treatment of chronic edema3 and recovery from lower extremity ulcers.45 It has also been found