基于平行光孔和针孔准直器的脑SPECT系统的贝叶斯图像重建算法.pdfVIP

中国科技论文在线 A Bayesian SPECT Image Reconstruction Algorithm for a High Resolution Brain Imaging System with Combined Parallel hole and Pinhole Collimation# * 5 Huang Qiu (School of Biomedical Engineering, Shanghai Jiao Tong University) Abstract : A brain single photon emission computed tomography (SPECT) imager is simulated for obtaining high resolution brain scans for various imaging diagnostic applications such as in diagnosing brain ischemia. In this simulation the camera consists of one large field of view detector with parallel 10 hole collimation and five smaller field of view high resolution detectors with pinhole collimation. The parallel hole collimation detector images the whole brain and acquires data without truncation. It localizes areas of particular diagnostic interest, and also provides support information for the reconstruction of data acquired by the pinhole collimation detectors. The five pinhole collimation detectors image small regions of the brain. They provide high resolution truncated projections, from 15 which high resolution region of interest (ROI) is obtained. The reconstruction is performed using a Bayesian estimate with total variation regularization within the ROI and the low resolution image from the parallel hole collimation detector as the prior information. The camera improves the quantitation for the interior problem. The combination of large field of view parallel hole collima