The role of Methyl-CpG Binding Protein 2 in Rett课件.pptVIP

The role of Methyl-CpG Binding Protein 2 in Rett Syndrome Jessica Connor Rett Syndrome is a neurodevelopmental disorder Hypotonia – loss of muscle tone Apraxia —inability to perform motor functions loss of use hands repetitive hand movements diminished eye contact gait abnormalities lack of speech development Other Symptoms autism like behaviors toe walking sleep problems cognitive disabilities seizures breathing problems teeth grinding difficulty chewing Rett syndrome is caused by mutations in the MECP2 gene MECP2 GO Terms Suggest Function Biological Process Negative regulation of trans