肾精亏虚证耳聋的临床治疗.DOCVIP

临床医学论文-肾精亏虚证耳聋的临床治疗 ??????????? 作者：马华安，严道南，曹济航，陈国丰 【关键词】? 感音神经性耳聋；,,双盲对照；,,中医药治疗 　　摘要：目的探讨补肾填髓结合益气活血法治疗肾精亏虚证耳聋的临床疗效。方法选取240例符合入选标准的病例，采用随机化方法分为试验组与对照组，各为120例。采用两级盲法设计，试验组选用补肾填髓结合益气活血法治疗，对照组选用补肾填髓法治疗。第45天对各项结果进行统计分析。结果两组痊愈率无明显差别，试验组的有效率明显高于对照组。结论治疗肾精亏虚证耳聋采用补肾填髓结合益气活血法效果更佳。 　　关键词：感音神经性耳聋；? 双盲对照；? 中医药治疗 　　Clinic Therapy on Sensorineural Deafness in Kidney Essence Vacuity. 　　Abstract：ObjectiveTo estimate the clinic effect about combing supplement the kidney and quicken the blood and boosting qi treating sensorineural deafness in kidney essence vacuity. Methods240 patients were selected according with scheme, adopting random principal, made 240 cases into two groups, experiment group and control group, two groups have equal cases. Two blind levels were used.?Experimental group adopted supplement the kidney and quicken the blood and boosting qi, control group adopted supplement the kidney. On 45th?day, static analysis was adopted according with the score. ResultsThere is no significant different in recovery between two groups .Experimental group has higher effective. ConclusionThere is better effective on combing supplement the kidney and quicken the bolld and boosting qi treating sensorineural deafness in kidney essence vacuity. 　　Key words：Sensorineural Deafness;? Two Blind control;? Therapy Traditional Chinese Medicine ??? 　　感音神经性聋现今仍是难治之疾病。现代医学加大对电子耳蜗、干细胞移植等前沿技术的研究，但此技术大量推广应用至临床仍需假以时日。中医中药在调养及用药的简便廉方面有自已独特的优势。根据中医“肾主耳”“肾开窍于耳”的理论，诊治时多治以补肾填髓法，但我们根据临床经验总结得出肾精亏虚证耳聋选用补肾填髓结合益气活血法更为有效。 　　1? 资料与方法 　　1.1? 试验设计类型原则与试验步骤 　　1.1.1? 试验设计类型随机平行组对照设计。 　　1.1.2? 试验设计原则病例数：试验组与对照组例数相等，各为120例，共240例。随机分组方法：采用随机化方法。借助SAS统计系统产生240例受试者所接受处理（试验组与对照组）的随机安排，即列出流水号01-240所对应的治疗分配。对照：试验组（A）选用炙淫羊藿307 g，制何首乌230 g，熟地黄230 g，制黄精230 g，醋炙龟甲460 g，煅磁石123 g，川芎230 g，郁金230 g，炙黄芪307 g，僵蚕153 g。以上10味共制得胶囊1000粒。对照组（B）选用耳聋左慈丸。耳聋左慈丸为2000年版《中国药典》及部颁标准收载品种，由磁石、熟地黄、山茱萸、牡丹皮、山药、茯苓、泽泻、竹叶、柴胡组成。盲法设计：采用两级盲法设计，第1级为各病例号所对应的组别，第2级为两组所对应的处理（试验组和对照组）。 　　1.2? 病例选择 　　1.2.1? 西医诊断标准感音神经性聋（非遗传性获得性感音神经性耳聋）?? 病史：因多种原因所致听力渐进性减退，或突发性