不同药物对烟雾吸入性损伤大鼠肺保护作用的研究.pdfVIP

() 2008 3 4 Ch in J Injury RepairW ound Healing(E lectron icVer ion), Augu t 2008, Vol 3, No. 4 433 刘群 冯世海 赵永健 施耘 李全 作者简介: 刘群, 男, 1956年生中华烧伤外科学会委员, 天津 烧伤外科分会副主 委, 天津 整形美容外科分会副主委, 天津医科大学硕士研究生导师天津 第四医院烧 伤整形科主任, 主任医师, 业务副院长研究方向: 吸入性损伤, 创面修复和瘢痕治疗从 事烧伤合并吸入性损伤的诊断和治疗研究, 在国内达领先水平, 获国家级 级科研成果 10项, 获省部级局级科技进步奖 8 项, 引进新技术填补天津 空白项目 10余项, 撰写专 业论文 40余篇发表于各专业期刊 ! SD 5, C, A DU , M 6 h ( TNF) 6 ( IL6) ( SOD )(MDA)( NO )( iNOS), C , M , , , UD M , U TNFIL6 MDA (P 0. 05), D(P 0. 01) C, A NOiNOSSOD (P 0. 05) DU iNOS C(P 0. 05) , ! ; ; ; P rotective effects of differen t agen ts on sm oke inhalation injury in rats m odel LIU Qun, FEN G Sh ihai, ZHA O Yong j ian, SH I Yun, LI Q uan. D ep ar tm ent o B urns, The F ourth H osp ital o T ianj in, T ianj in B urns Institute, T ianj in 300222, Ch ina Abstract! Objective To evaluate the protective effect of ulina tatin, dexam etha one and am broxol on m oke inhalation ingury u ing rat m ode.l M ethods F ifty rat w ere random ly divided into five group . The rat in control group ( group C) w ere : ( No. 06KG06) : 300222 : Em ail: h ellotianjin@ yahoo. com. cn 434 () 2008 3 4 Ch in J Injury RepairW ound H ealing(E lectron icVer ion), Augu t 2008, Vol 3, No. 4 not expo ed to m oke. The rem aining four group w ere labeled group A, group D, group U and group M and then treated w ith am briox,l dexam etha one, ulina tatin, and norm al aline re pectively. The e four group w ere treated after half an hour from the on et of m oke inhalation injury and all rat w ere acrificed after a period of ix hour . Arterial b lood w a collected from the rat and then the level of tum or necro i factor ( TNF) and interleu