金属锡参与的水相Barbier-Grignard反应及基不对称反应的初探.pdf

Abstract Inthe first the ReactionofTininthemoderate article，We Barbier—Grigard report with and ferric reacts bromide chloride，tinsmoothly condition．Catalyzed allyl by function as inthe is suchmethyl water,and group aldehydes yieldgood．The halidedonot thereaction．Thofd、Bunsaturatedis methoxyl affect yield aldehyde also functionis reactionis reasonis good．While nitro，the stopped．The group Bromidecanalsoacceleratethe reaction． unclear．Tetraethylammonium allylation The is toexcellent．Atthesame enantioselectiveTin-mediated yieldgood time，the reactionof bromideto was of its allyl aldehydesinvestigated．Because goodsolubility inwaterChiral derivatedfrom was no was ligands used，but results prolinol good obtained． Tin Reaction medium KeywordsBarbier-Grigard Allylation Aqueous 立墅查兰垂鲞宣垫垡堂堕堡：!：堕塑竺兰些丝苎———————————一 第一章 前 言 1834年，Farady，M．最早报道了水相中形成