下颌升支矢状劈开截骨术与下颌角整形术同期进行的骨愈合动物实验研究.docVIP

下颌升支矢状劈开截骨术与下颌角整形术同期进行的骨愈合动物实验研究 杨东昆1，王涛2，毛晓斌，张桂梅，刘鹏 （重庆医科大学附属口腔医院口腔颌面外科，重庆 400015) 【摘 要】通过对兔同期行下颌骨切开术与咀嚼肌剥离术，模拟下颌升支矢状劈开截骨术与下颌角整形术同期手术。对比观察术后骨愈合情况，从而推测其可行性。选取18只健康新西兰大白兔，随机分为3组，实验组（n=8）一侧行下颌骨切术与咀嚼肌剥离术同期手术，对侧不手术；对照组(n=8)一侧行下颌骨切开术，对侧不手术；正常对照组(n=2)不行任何手术。对比观察术后2 w、4w、8w、12w手术侧骨愈合情况。实验组与对照组骨愈合过程相似，12w时各组兔骨小梁矿化度无显著差异。下颌骨切开术与咀嚼肌剥离术同期进行，其术后骨断端达到骨愈合，具有可行性。 R782.2+3 【文献标志码】A 【收稿日期】2011- 05- 27 The study for bone healing of simultaneous mandibular sagittal split osteotomy and mandibular angloplasty in animals Yang Dong-kun，Department of Dentofacial Surgery, the Affiliated Stomatology Hospital, Chongqing Medical University) 【Abstracts】 Objective: To simulate the simultaneous operation of mandibular sagittal split osteotomy and mandibular angloplasty, through we perform mandibular osteotomy and masticatory muscle dissection on rabbits over the same period. Comparing and observing the situation of bone healing after surgery, then we can speculate that the feasibility of the simultaneous operation. Methods: 18 healthy New Zealand white rabbits were selected and randomly divided into three groups. For the experimental group, mandibular osteotomy and masticatory muscle dissection were performed on one side of mandible over the same period and the opposite wasn’t. For the control group, mandibular osteotomy was performed on one side of mandible and the opposite wasn’t. Normal control group(n=2)was done without surgery .Then we observed the situation of bone healing at the surgical side in both groups at 2nd week, 4th week, 8th week and 12th week after surgery. Results: The process of bone healing in the experimental group was similar to the control group. And at 12th week, trabecular bone in rabbits of each group had no significant difference in degree of mineralization. Conclusion: Mandibular osteotomy and masticatory muscle dissection can be performed over the same period, and mandibular fractures can heal up to bony union after surgery. The simultaneous op